EXEL Exelixis margins

Relative Growth: Rel. Growth: 96

Relative Strength: Rel. Strength: 95

Relative Valuation: Rel. Valuation: 58

Relative Profitability: Rel. Profitability: 98

Gross margin

96.3%

Operating margin

40.2%

EBITDA margin

44.8%

Net margin

35.5%

The Exelixis shows a gross margin of 96.3%, an operating margin of 40.2%, an EBITDA margin of 44.8%, and a net margin of 35.5%. Net margin showed the largest year-over-year gain at 5.9 percentage points, whereas gross margin showed the largest decline at 0.3 percentage points.

EXEL margin history

Gross, operating, EBITDA and net margin trends

Over the last 3 years, Exelixis's margins averaged 96.35% gross, 28.88% operating, 34.85% EBITDA, and 25.88% net. The current figures show operating, EBITDA, and net margins are above their three-year averages, while gross margin is below its three-year average.

EXEL margin expansion

Year-over-year margin changes in percentage points

The strongest improvement was in net margin, which increased by 5.9 percentage points, and operating margin also expanded by 5.2 percentage points and EBITDA margin also expanded by 4.3 percentage points, whereas gross margin contracted by 0.3 percentage points.

Gross margin expansion

-0.3pp

Operating margin expansion

5.2pp

EBITDA margin expansion

4.3pp

Net margin expansion

5.9pp

EXEL Gross margin

Over the last 3 years, the average gross margin for Exelixis was 96.35%. The current gross margin of 96.3% is 0.1 percentage points below its three-year average. Exelixis's gross margin ranged from a low of 95.7% in Mar 2024 to a high of 96.8% in Mar 2025.

EXEL Operating margin

Over the last 3 years, Exelixis's operating margin averaged 28.88%. Right now, Exelixis's current operating margin is 40.2%, which is 11.3 percentage points above its three-year average. During this period, operating margin reached a high of 40.2% in Sep 2026 and a low of 9.3% in Dec 2023.

EXEL EBITDA margin

Exelixis's EBITDA margin averaged 34.85% across the past 3 years. Compared with its three-year average, Exelixis's current EBITDA margin is 44.8% and is 10 percentage points above its three-year average. Over the last 3 years, Exelixis's EBITDA margin peaked at 44.8% in Sep 2026 and reached a low of 16.9% in Mar 2024.

EXEL Net margin

Over the last 3 years, Exelixis's net margin averaged 25.88%. As of the latest period, Exelixis's current net margin is 35.5%, which is 9.6 percentage points above its three-year average. During this period, net margin reached a high of 35.5% in Sep 2026 and a low of 11.1% in Mar 2024.

EXEL margin group comparison

Margins compared with peer-group, industry and sector averages

With a gross margin of 96.3%, EXEL stands higher than the Healthcare sector, the industry and its peers average. Looking at the Healthcare sector average of 68.3%, Exelixis's gross margin is 41% higher.

EXEL margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Exelixis's gross margin?

As of Sep 30, 2026, EXEL has a gross margin of 96.3%.

What is Exelixis's operating margin?

As of Sep 30, 2026, EXEL has an operating margin of 40.2%.

What is Exelixis's EBITDA margin?

The current EBITDA margin for EXEL is 44.8% as of Sep 30, 2026.

What is Exelixis's net margin?

The current net margin for EXEL is 35.5% as of Sep 30, 2026.

What are the average margins of EXEL?

Across the last 3 years, EXEL averaged 96.4% gross, 28.9% operating, 34.9% EBITDA, and 25.9% net.

What are the highest historical margins of EXEL?

Over this 5-year history, EXEL peaked at 96.8% gross in Mar 2025, 40.2% operating in Sep 2026, 44.8% EBITDA in Sep 2026, and 35.5% net in Sep 2026.

What are the lowest historical margins of EXEL?

In the last 5 years, the lowest margins reported by EXEL were 95.7% gross in Mar 2024, 2.3% operating in Sep 2023, 9.9% EBITDA in Sep 2023, and 5.2% net in Sep 2023.