EXEL
Exelixis
PE ratio, current and historical analysis
- Stocks
- Healthcare
- NASDAQ: EXEL
- PE Ratio
As at Jul 2, 2026, the EXEL stock has a PE ratio of 17.9. This is based on the current EPS of $3.12 and the stock price of $55.85 per share. An increase of 8% has been recorded in the P/E ratio compared to the average of 16.6 of the last 4 quarters.
EXEL PE ratio history
The mean historical PE ratio of Exelixis over the last ten years is 50.7. The current 17.9 PE ratio is 65% below the historical average. In the past ten years, EXEL's PE ratio was at its highest in the Mar 2017 quarter at 722.33, with a price of $21.67 and an EPS of $0.03. The Dec 2018 quarter recorded the bottom point at 8.48, with a price of $19.67 and an EPS of $2.32.
Exelixis PE ratio by year
Maximum annual increase: 235.44% in 2020
Maximum annual decrease: -85.49% in 2018
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| 2025 | 15.22 | -17.73% | $43.83 | $2.88 |
| 2024 | 18.5 | -49.88% | $33.3 | $1.8 |
| 2023 | 36.91 | 31.17% | $23.99 | $0.65 |
| 2022 | 28.14 | 12.38% | $16.04 | $0.57 |
| 2021 | 25.04 | -55.09% | $18.28 | $0.73 |
| 2020 | 55.75 | 235.44% | $20.07 | $0.36 |
| 2019 | 16.62 | 95.99% | $17.62 | $1.06 |
| 2018 | 8.48 | -85.49% | $19.67 | $2.32 |
| 2017 | 58.46 | N/A | $30.4 | $0.52 |
| 2016 | N/A | N/A | $14.91 | -$0.28 |
| 2015 | N/A | N/A | $5.64 | -$0.77 |
| 2014 | N/A | N/A | $1.44 | -$1.34 |
| 2013 | N/A | N/A | $6.13 | -$1.33 |
| 2012 | N/A | N/A | $4.57 | -$0.92 |
| 2011 | 7.89 | N/A | $4.74 | $0.6 |
Exelixis PE ratio by quarter (TTM)
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| Mar 2026 | 13.75 | -9.66% | $42.89 | $3.12 |
| Dec 2025 | 15.22 | -9.35% | $43.83 | $2.88 |
| Sep 2025 | 16.79 | -18.1% | $41.3 | $2.46 |
| Jun 2025 | 20.5 | 24.92% | $44.08 | $2.15 |
| Mar 2025 | 16.41 | -11.3% | $36.92 | $2.25 |
| Dec 2024 | 18.5 | 12.67% | $33.3 | $1.8 |
| Sep 2024 | 16.42 | -14.52% | $25.95 | $1.58 |
| Jun 2024 | 19.21 | -48.19% | $22.47 | $1.17 |
| Mar 2024 | 37.08 | 0.46% | $23.73 | $0.64 |
| Dec 2023 | 36.91 | -52.7% | $23.99 | $0.65 |
| Sep 2023 | 78.04 | 108.27% | $21.85 | $0.28 |
| Jun 2023 | 37.47 | -7.34% | $19.11 | $0.51 |
| Mar 2023 | 40.44 | 43.71% | $19.41 | $0.48 |
| Dec 2022 | 28.14 | 72.32% | $16.04 | $0.57 |
| Sep 2022 | 16.33 | -33.32% | $15.68 | $0.96 |
EXEL Price vs fair value
EXEL average PE ratio chart
What this chart measures
The Historical Valuation Regime chart shows where the stock's current valuation sits relative to its own historical valuation range over the selected lookback period.
This is a history-relative tool, not a market-relative percentile. It does not compare the stock to other companies. Instead, it compares each historical valuation reading to the stock's own past readings.
Percentile logic
The threshold lines are calculated them from the stock's real historical values using percentile interpolation. That is why some colored bands are narrow while others are wide: the band widths reflect how the stock actually traded through time.
Regime map
| Historical percentile | Regime | Chart meaning |
|---|---|---|
| 0-10 | Historically Low | Deep cheap zone |
| >10-25 | Below Average | Cheap relative to history |
| >25-75 | Average | Within the normal historical range |
| >75-90 | Above Average | Expensive relative to history |
| >90-100 | Historically High | Extreme or stretched valuation |
How to read each part
| Chart element | What it tells you |
|---|---|
| Main line | The actual historical valuation values over time for the selected metric. |
| Dashed horizontal lines | The stock's computed P10, P25, Median, P75, and P90 thresholds for the selected period. |
| Colored bands | The historical valuation zones between those thresholds. |
| Metric boxes | Current ratio, historical median, current percentile, and current regime. |
| Timeline strip | A condensed regime history showing how the stock moved between cheap, fair, and expensive states across each observation. |
Important metric definitions
Current Percentile is the percentile rank of the latest valid historical observation within the selected lookback range.
Current Regime is assigned directly from the latest observation's percentile bucket using the fixed 10 / 25 / 75 / 90 cutoffs shown above.
How to use it well
This chart is most useful for answering a narrow question: Is this stock trading high, low, or normal relative to its own history? It works best alongside growth, profitability, and forward-looking business analysis, because a stock can deserve a higher or lower regime if its business quality has changed.
EXEL's current P/E ratio is lower than the 3, 5 and 10-year averages.
PE comparison
With a P/E of 17.9, EXEL stands above the industry average but below the Healthcare sector and its peers average. Compared to its Healthcare sector average of 26.04, Exelixis's P/E is 31% lower.
EXEL PE vs peers
EXEL's PE ratio is lower than its peer stocks JNJ and MRK, but it is greater than BMY's. Exelixis's current PE ratio of 17.9 is below the average of its peers, which is 25.42.
| Stock name | PE ratio | Market cap |
|---|---|---|
| BMY Bristol Myers Squibb Co | 16.28 | $118.71B |
| EXEL Exelixis Inc | 17.9 | $14.04B |
| PFE Pfizer Inc | 18.56 | $138.61B |
| AMGN Amgen Inc | 25.84 | $201.93B |
| JNJ Johnson & Johnson | 30.13 | $633.19B |
| MRK Merck & Co Inc | 36.29 | $319.99B |
| CRIS Curis Inc | N/A | $13.51M |
Frequently asked questions
What is Exelixis's PE ratio?
EXEL stock has a price to earnings ratio of 17.9 as of Jul 2, 2026.
What is the 3-year average PE ratio for Exelixis (EXEL)?
The 3-year average PE ratio for EXEL stock is 26.26.
What is the 5-year average PE ratio for Exelixis (EXEL)?
The 5-year average PE ratio for EXEL stock is 27.62.
What is the highest PE ratio for EXEL?
In the last ten years, the Mar 2017 quarter recorded the highest quarterly PE ratio at 722.33.
How does the current PE ratio for EXEL compare to its historical average?
EXEL's current price to earnings ratio is 65% below its 10-year historical average.
How is EXEL's PE ratio calculated (Exelixis PE ratio formula)?
The PE ratio is calculated by taking the latest stock price and dividing it by the EPS for the last 12 months. As of today (Jul 2, 2026), Exelixis's stock price is $55.85. The earnings per share for the trailing twelve months (TTM) ending Mar 2026 is $3.12. Therefore, Exelixis's P/E ratio for today is 17.9. PE RATIO(17.9) = STOCK PRICE($55.85) / TTM EPS($3.12)
All PE ratio stats are based on quarterly TTM periods, unless otherwise specified.