XNCR Xencor margins

Relative Growth: Rel. Growth: 64

Relative Strength: Rel. Strength: 99

Relative Valuation: Rel. Valuation: 6

Relative Profitability: Rel. Profitability: 40

Gross margin

100%

Operating margin

-72.7%

EBITDA margin

-41%

Net margin

-58.8%

Currently, Xencor has a gross margin of 100%, an operating margin of -72.7%, an EBITDA margin of -41%, and a net margin of -58.8%; its operating margin is negative at -72.7%, its EBITDA margin is negative at -41%, and its net margin is negative at -58.8%. The largest improvement was in net margin, up 28.3 percentage points; the remaining margins held steady.

XNCR margin history

Gross, operating, EBITDA and net margin trends

Xencor's margins averaged 100% gross, -129.22% operating, -92.86% EBITDA, and -127.22% net over the last 3 years. Compared with the three-year averages, operating, EBITDA, and net margins are above their three-year averages.

XNCR margin expansion

Year-over-year margin changes in percentage points

From the same period last year, operating margin expanded by 18.6 percentage points, EBITDA margin by 15.6 percentage points, and net margin by 28.3 percentage points, while gross margin was unchanged.

Gross margin expansion

0pp

Operating margin expansion

18.6pp

EBITDA margin expansion

15.6pp

Net margin expansion

28.3pp

XNCR Gross margin

Over the last 3 years, Xencor's gross margin averaged 100%. Right now, Xencor's current gross margin is 100%, which is in line with its three-year average. During this period, gross margin reached a high of 100% in Sep 2026 and a low of 100% in Dec 2023.

XNCR Operating margin

Xencor's operating margin averaged -129.22% across the past 3 years. Compared with its three-year average, Xencor's current operating margin is -72.7% and is 56.5 percentage points above its three-year average. Over the last 3 years, Xencor's operating margin peaked at -72.7% in Sep 2026 and reached a low of -217.9% in Mar 2026.

XNCR EBITDA margin

Over the last 3 years, Xencor's EBITDA margin averaged -92.86%. The current EBITDA margin of -41% is 51.9 percentage points above its three-year average. During this period, EBITDA margin reached a high of -37.4% in Dec 2025 and a low of -164.9% in Dec 2024.

XNCR Net margin

Over the last 3 years, Xencor's net margin averaged -127.22%. Currently, Xencor's current net margin is -58.8%, which is 68.4 percentage points above its three-year average. During this period, net margin reached a high of -58.8% in Sep 2026 and a low of -210.5% in Dec 2024.

XNCR margin group comparison

Margins compared with peer-group, industry and sector averages

With a gross margin of 100%, XNCR stands higher than the Healthcare sector, the industry and its peers average. Looking at the Healthcare sector average of 68.4%, Xencor's gross margin is 46% higher.

XNCR margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Xencor's gross margin?

For the period ending Sep 30, 2026, XNCR recorded a gross margin of 100%.

What is Xencor's operating margin?

As of Sep 30, 2026, XNCR has a negative operating margin of -72.7%.

What is Xencor's EBITDA margin?

As of Sep 30, 2026, XNCR has a negative EBITDA margin of -41%.

What is Xencor's net margin?

For the period ending Sep 30, 2026, XNCR recorded a net margin of -58.8%.

What are the average margins of XNCR?

The three-year average margins for XNCR were 100.0% gross, -129.2% operating, -92.9% EBITDA, and -127.2% net.

What are the highest historical margins of XNCR?

Over the last 5 years, Xencor's highest margins were 100% gross in Sep 2026, 26.3% operating in Mar 2022, 35.7% EBITDA in Mar 2022, and 33.3% net in Mar 2022.

What are the lowest historical margins of XNCR?

Over this 5-year history, Xencor's margins fell as low as 100% gross in Dec 2021, -217.9% operating in Mar 2026, -164.9% EBITDA in Dec 2024, and -210.5% net in Dec 2024.