SRPT Sarepta Therapeutics margins

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Relative Growth: Rel. Growth: 10
Relative Strength: Rel. Strength: 45
Relative Valuation: Rel. Valuation: 26
Relative Profitability: Rel. Profitability: 26
Gross margin
59.1%
Operating margin
-7.3%
EBITDA margin
-3.7%
Net margin
-6.9%

At present, Sarepta Therapeutics currently has a gross margin of 59.1%, an operating margin of -7.3%, an EBITDA margin of -3.7%, and a net margin of -6.9%; its operating margin is negative at -7.3%, its EBITDA margin is negative at -3.7%, and its net margin is negative at -6.9%. Gross margin had the largest decline, decreasing by 20.2 percentage points, while the other available margins also declined.

SRPT margin history

Gross, operating, EBITDA and net margin trends

Sarepta Therapeutics's margins averaged 77.7% gross, -5.53% operating, -3.25% EBITDA, and -7.27% net during the last 3 years. Sarepta Therapeutics's current metrics show that net margin is above its three-year average and gross, operating, and EBITDA margins are below their three-year averages.

SRPT margin expansion

Year-over-year margin changes in percentage points

Sarepta Therapeutics's gross margin contracted by 20.2 percentage points, operating margin by 7.3 percentage points, EBITDA margin by 5 percentage points, and net margin by 4.6 percentage points, led by gross margin with a decline of 20.2 percentage points.

Gross margin expansion
-20.2pp
Operating margin expansion
-7.3pp
EBITDA margin expansion
-5pp
Net margin expansion
-4.6pp

SRPT Gross margin

Over the last 3 years, the average gross margin for Sarepta Therapeutics was 77.7%. The latest gross margin for Sarepta Therapeutics is 59.1%, 18.6 percentage points below its three-year average. Sarepta Therapeutics's gross margin ranged from a low of 59.1% in Jun 2026 to a high of 88.3% in Jun 2024.

SRPT Operating margin

Looking at the last 3 years, Sarepta Therapeutics had an average operating margin of -5.53%. Against its three-year average, Sarepta Therapeutics's operating margin is currently -7.3%, 1.8 percentage points below its three-year average. Looking back over the last 3 years, Sarepta Therapeutics's operating margin reached 11.5% at its highest point in Dec 2024 and -31.8% at its lowest in Dec 2025.

SRPT EBITDA margin

Across the last 3 years, Sarepta Therapeutics had an average EBITDA margin of -3.25%. Against its three-year average, Sarepta Therapeutics's EBITDA margin is currently -3.7%, 0.5 percentage points below its three-year average. Looking back over the last 3 years, Sarepta Therapeutics's EBITDA margin reached 16.5% at its highest point in Dec 2024 and -37.1% at its lowest in Dec 2023.

SRPT Net margin

Over the last 3 years, the average net margin for Sarepta Therapeutics was -7.27%. The latest net margin for Sarepta Therapeutics is -6.9%, 0.4 percentage points above its three-year average. Sarepta Therapeutics's net margin ranged from a low of -43.1% in Dec 2023 to a high of 12.4% in Dec 2024.

SRPT margin group comparison

Margins compared with peer-group, industry and sector averages

Sarepta Therapeutics's gross margin of 59.1% is below the Healthcare sector, the industry and its peers average. Compared to its Healthcare sector average of 68.3%, Sarepta Therapeutics's gross margin is 13% lower.

SRPT margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Sarepta Therapeutics's gross margin?

As of Jun 30, 2026, SRPT has a gross margin of 59.1%.

What is Sarepta Therapeutics's operating margin?

As of Jun 30, 2026, SRPT has an operating margin of -7.3%.

What is Sarepta Therapeutics's EBITDA margin?

For the period ending Jun 30, 2026, SRPT recorded an EBITDA margin of -3.7%.

What is Sarepta Therapeutics's net margin?

As of Jun 30, 2026, SRPT has a negative net margin of -6.9%.

What are the average margins of SRPT?

The three-year average margins for SRPT were 77.7% gross, -5.5% operating, -3.3% EBITDA, and -7.3% net.

What are the highest historical margins of SRPT?

Within the 5-year period, SRPT recorded its highest margins at 88.3% gross in Jun 2024, 11.5% operating in Dec 2024, 16.5% EBITDA in Dec 2024, and 12.4% net in Dec 2024.

What are the lowest historical margins of SRPT?

Looking back across 5 years, SRPT reached its lowest margins at 59.1% gross in Jun 2026, -65.5% operating in Dec 2021, -107% EBITDA in Mar 2023, and -114.3% net in Mar 2023.