SRPT Sarepta Therapeutics margins

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Relative Growth: Rel. Growth: 45
Relative Strength: Rel. Strength: 37
Relative Valuation: Rel. Valuation: 42
Relative Profitability: Rel. Profitability: 49
Gross margin
56.8%
Operating margin
-2.5%
EBITDA margin
4.2%
Net margin
0.8%

At present, Sarepta Therapeutics currently has a gross margin of 56.8%, an operating margin of -2.5%, an EBITDA margin of 4.2%, and a net margin of 0.8%; its operating margin is negative at -2.5%. The strongest positive change was in net margin, higher by 6.7 percentage points. The strongest negative change was in gross margin, lower by 19.5 percentage points.

SRPT margin history

Gross, operating, EBITDA and net margin trends

Sarepta Therapeutics's margins averaged 75.96% gross, -5.28% operating, -1.14% EBITDA, and -5.13% net during the last 3 years. Sarepta Therapeutics's current metrics show that operating, EBITDA, and net margins are above their three-year averages and gross margin is below its three-year average.

SRPT margin expansion

Year-over-year margin changes in percentage points

Sarepta Therapeutics's operating margin expanded by 2.7 percentage points, EBITDA margin by 6.6 percentage points, and net margin by 6.7 percentage points, but gross margin contracted by 19.5 percentage points.

Gross margin expansion
-19.5pp
Operating margin expansion
2.7pp
EBITDA margin expansion
6.6pp
Net margin expansion
6.7pp

SRPT Gross margin

Over the last 3 years, the average gross margin for Sarepta Therapeutics was 75.96%. The latest gross margin for Sarepta Therapeutics is 56.8%, 19.2 percentage points below its three-year average. Sarepta Therapeutics's gross margin ranged from a low of 56.8% in Sep 2026 to a high of 88.3% in Jun 2024.

SRPT Operating margin

Looking at the last 3 years, Sarepta Therapeutics had an average operating margin of -5.28%. Against its three-year average, Sarepta Therapeutics's operating margin is currently -2.5%, 2.8 percentage points above its three-year average. Looking back over the last 3 years, Sarepta Therapeutics's operating margin reached 11.5% at its highest point in Dec 2024 and -31.8% at its lowest in Dec 2025.

SRPT EBITDA margin

Across the last 3 years, Sarepta Therapeutics had an average EBITDA margin of -1.14%. Against its three-year average, Sarepta Therapeutics's EBITDA margin is currently 4.2%, 5.3 percentage points above its three-year average. Looking back over the last 3 years, Sarepta Therapeutics's EBITDA margin reached 16.5% at its highest point in Dec 2024 and -37.1% at its lowest in Dec 2023.

SRPT Net margin

Over the last 3 years, the average net margin for Sarepta Therapeutics was -5.13%. The latest net margin for Sarepta Therapeutics is 0.8%, 5.9 percentage points above its three-year average. Sarepta Therapeutics's net margin ranged from a low of -43.1% in Dec 2023 to a high of 12.4% in Dec 2024.

SRPT margin group comparison

Margins compared with peer-group, industry and sector averages

Sarepta Therapeutics's gross margin of 56.8% is below the Healthcare sector, the industry and its peers average. Compared to its Healthcare sector average of 68.4%, Sarepta Therapeutics's gross margin is 17% lower.

SRPT margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Sarepta Therapeutics's gross margin?

As of Sep 30, 2026, SRPT has a gross margin of 56.8%.

What is Sarepta Therapeutics's operating margin?

As of Sep 30, 2026, SRPT has an operating margin of -2.5%.

What is Sarepta Therapeutics's EBITDA margin?

For the period ending Sep 30, 2026, SRPT recorded an EBITDA margin of 4.2%.

What is Sarepta Therapeutics's net margin?

The current net margin for SRPT is 0.8% as of Sep 30, 2026.

What are the average margins of SRPT?

The three-year average margins for SRPT were 76.0% gross, -5.3% operating, -1.1% EBITDA, and -5.1% net.

What are the highest historical margins of SRPT?

Within the 5-year period, SRPT recorded its highest margins at 88.3% gross in Jun 2024, 11.5% operating in Dec 2024, 16.5% EBITDA in Dec 2024, and 12.4% net in Dec 2024.

What are the lowest historical margins of SRPT?

Looking back across 5 years, SRPT reached its lowest margins at 56.8% gross in Sep 2026, -65.5% operating in Dec 2021, -107% EBITDA in Mar 2023, and -114.3% net in Mar 2023.