Currently, Ptc Therapeutics shows a gross margin of 93.2%, an operating margin of 12.8%, an EBITDA margin of 15.7%, and a net margin of -9.2%; its net margin is negative at -9.2%. Each available margin deteriorated from the same period last year. Net margin recorded the strongest contraction, dropping by 51.5 percentage points.
Ptc Therapeutics's margins averaged 94.18% gross, 0.23% operating, 11% EBITDA, and -13.54% net during the last 3 years. Against the three-year averages, operating, EBITDA, and net margins are above their three-year averages and gross margin is below its three-year average.
The biggest contraction was in net margin, which fell by 51.5 percentage points. The other available margins also declined.
Ptc Therapeutics's gross margin averaged 94.18% in the last 3 years. Compared with its three-year average, Ptc Therapeutics's current gross margin is 93.2% and is 1 percentage points below its three-year average. Over the last 3 years, Ptc Therapeutics's gross margin peaked at 97.3% in Dec 2025 and reached a low of 92.2% in Sep 2024.
Over the last 3 years, the average operating margin for Ptc Therapeutics was 0.23%. The latest operating margin for Ptc Therapeutics is 12.8%, 12.6 percentage points above its three-year average. Ptc Therapeutics's operating margin ranged from a low of -60.5% in Dec 2023 to a high of 50% in Dec 2025.
Ptc Therapeutics recorded an average EBITDA margin of 11% across the last 3 years. Compared with its three-year average, Ptc Therapeutics's current EBITDA margin is 15.7% and is 4.7 percentage points above its three-year average. Ptc Therapeutics's EBITDA margin ranged from a low of -34.2% in Dec 2023 to a high of 51.7% in Dec 2025.
The average net margin for Ptc Therapeutics was -13.54% in the last 3 years. Currently, the current net margin for Ptc Therapeutics is -9.2%, 4.3 percentage points above its three-year average. The net margin for Ptc Therapeutics moved between -66.8% in Dec 2023 and 42.3% in Sep 2025.
With a gross margin of 93.2%, PTCT stands higher than the Healthcare sector, the industry and its peers average. Looking at the Healthcare sector average of 68.4%, Ptc Therapeutics's gross margin is 36% higher.
For the period ending Sep 30, 2026, PTCT recorded a gross margin of 93.2%.
As of Sep 30, 2026, PTCT has an operating margin of 12.8%.
The current EBITDA margin for PTCT is 15.7% as of Sep 30, 2026.
The current net margin for PTCT is -9.2% as of Sep 30, 2026.
The three-year average margins for PTCT were 94.2% gross, 0.2% operating, 11.0% EBITDA, and -13.5% net.
Ptc Therapeutics's highest recorded margins during the past 5 years were 97.3% gross in Dec 2025, 50% operating in Dec 2025, 51.7% EBITDA in Dec 2025, and 42.3% net in Sep 2025.
Looking back across 5 years, PTCT reached its lowest margins at 92.2% gross in Sep 2024, -95.8% operating in Sep 2023, -67% EBITDA in Dec 2021, and -97.3% net in Dec 2021.