OPK Opko Health margins

Relative Growth: Rel. Growth: 8

Relative Strength: Rel. Strength: 89

Relative Valuation: Rel. Valuation: 16

Relative Profitability: Rel. Profitability: 29

Gross margin

46.2%

Operating margin

-25.5%

EBITDA margin

-9%

Net margin

-29.5%

Opko Health shows a gross margin of 46.2%, an operating margin of -25.5%, an EBITDA margin of -9%, and a net margin of -29.5%, although its operating margin is negative at -25.5%, its EBITDA margin is negative at -9%, and its net margin is negative at -29.5%. Operating margin improved the most, by 9.9 percentage points, while EBITDA margin declined the most, by 12.2 percentage points.

OPK margin history

Gross, operating, EBITDA and net margin trends

Over the last 3 years, Opko Health's margins averaged 35% gross, -26.28% operating, -0.65% EBITDA, and -25.37% net. Currently, gross and operating margins are above their three-year averages, while EBITDA and net margins are below their three-year averages.

OPK margin expansion

Year-over-year margin changes in percentage points

Opko Health's gross margin expanded by 7.5 percentage points, operating margin by 9.9 percentage points, and net margin by 3.5 percentage points, but EBITDA margin contracted by 12.2 percentage points.

Gross margin expansion

7.5pp

Operating margin expansion

9.9pp

EBITDA margin expansion

-12.2pp

Net margin expansion

3.5pp

OPK Gross margin

The average gross margin for Opko Health was 35% during the last 3 years. At present, the current gross margin for Opko Health is 46.2%, 11.2 percentage points above its three-year average. The gross margin for Opko Health moved between 25.1% in Sep 2024 and 46.2% in Sep 2026.

OPK Operating margin

Over the last 3 years, the average operating margin for Opko Health was -26.28%. The latest operating margin for Opko Health is -25.5%, 0.8 percentage points above its three-year average. Opko Health's operating margin ranged from a low of -37.6% in Mar 2026 to a high of -18.2% in Dec 2023.

OPK EBITDA margin

Over the last 3 years, Opko Health recorded an average EBITDA margin of -0.65%. Compared with its three-year average, Opko Health's current EBITDA margin is -9% and is 8.4 percentage points below its three-year average. The highest EBITDA margin for Opko Health was 21.8% in Mar 2025, while the lowest was -16.7% in Jun 2024.

OPK Net margin

Opko Health's net margin averaged -25.37% over the last 3 years. Compared with its three-year average, Opko Health's current net margin is -29.5% and is 4.1 percentage points below its three-year average. Over the last 3 years, Opko Health's net margin peaked at -5.7% in Mar 2025 and reached a low of -43.8% in Mar 2026.

OPK margin group comparison

Margins compared with peer-group, industry and sector averages

Opko Health's gross margin of 46.2% is below the Healthcare sector, the industry and its peers average. Compared to its Healthcare sector average of 68.3%, Opko Health's gross margin is 32% lower.

OPK margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Opko Health's gross margin?

As of Sep 30, 2026, OPK has a gross margin of 46.2%.

What is Opko Health's operating margin?

As of Sep 30, 2026, OPK has an operating margin of -25.5%.

What is Opko Health's EBITDA margin?

The current EBITDA margin for OPK is -9% as of Sep 30, 2026.

What is Opko Health's net margin?

As of Sep 30, 2026, OPK has a negative net margin of -29.5%.

What are the average margins of OPK?

Over the last 3 years, Opko Health's margins averaged 35.0% gross, -26.3% operating, -0.7% EBITDA, and -25.4% net.

What are the highest historical margins of OPK?

Across the 5-year period, OPK posted its highest margins at 46.2% gross in Sep 2026, 1.1% operating in Dec 2021, 21.8% EBITDA in Mar 2025, and -1.7% net in Dec 2021.

What are the lowest historical margins of OPK?

Over this 5-year history, Opko Health's margins fell as low as 25.1% gross in Sep 2024, -37.6% operating in Mar 2026, -27% EBITDA in Dec 2022, and -43.8% net in Mar 2026.