IRWD
Ironwood Pharmaceuticals
PE ratio, current and historical analysis
- Stocks
- Healthcare
- NASDAQ: IRWD
- PE Ratio
As at Sep 23, 2026, the IRWD stock has a PE ratio of 5.34. This is based on the current EPS of $0.8 and the stock price of $4.27 per share. A decrease of 47% has been seen in the P/E ratio compared to the average of 10.0 of the last 4 quarters.
IRWD PE ratio history
The mean historical PE ratio of Ironwood Pharmaceuticals over the last seven years is 41.0. The current 5.34 PE ratio is 87% below the historical average. Over the past seven years, IRWD's PE ratio was at its highest in the Dec 2024 quarter at 443, with a price of $4.43 and an EPS of $0.01. The Dec 2021 quarter recorded the bottom point at 3.58, with a price of $11.66 and an EPS of $3.26.
Ironwood Pharmaceuticals PE ratio by year
Maximum annual increase: 206.15% in 2022
Maximum annual decrease: -94.93% in 2025
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| 2025 | 22.47 | -94.93% | $3.37 | $0.15 |
| 2024 | 443 | N/A | $4.43 | $0.01 |
| 2023 | N/A | N/A | $11.44 | -$6.45 |
| 2022 | 10.96 | 206.15% | $12.39 | $1.13 |
| 2021 | 3.58 | -78.94% | $11.66 | $3.26 |
| 2020 | 17 | -82.12% | $11.39 | $0.67 |
| 2019 | 95.07 | N/A | $13.31 | $0.14 |
| 2018 | N/A | N/A | $10.36 | -$1.85 |
| 2017 | N/A | N/A | $14.99 | -$0.78 |
| 2016 | N/A | N/A | $15.29 | -$0.56 |
| 2015 | N/A | N/A | $11.59 | -$1 |
| 2014 | N/A | N/A | $15.32 | -$1.39 |
| 2013 | N/A | N/A | $11.61 | -$2.35 |
| 2012 | N/A | N/A | $11.08 | -$0.68 |
| 2011 | N/A | N/A | $11.97 | -$0.65 |
Ironwood Pharmaceuticals PE ratio by quarter (TTM)
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| Jun 2026 | 5.26 | -4.01% | $4.21 | $0.8 |
| Mar 2026 | 5.48 | -75.61% | $3.51 | $0.64 |
| Dec 2025 | 22.47 | 226.12% | $3.37 | $0.15 |
| Sep 2025 | 6.89 | N/A | $1.31 | $0.19 |
| Jun 2025 | N/A | N/A | $0.72 | -$0.04 |
| Mar 2025 | N/A | N/A | $1.47 | -$0.2 |
| Dec 2024 | 443 | N/A | $4.43 | $0.01 |
| Sep 2024 | N/A | N/A | $4.12 | -$0.02 |
| Jun 2024 | 108.67 | N/A | $6.52 | $0.06 |
| Mar 2024 | N/A | N/A | $8.71 | -$6.77 |
| Dec 2023 | N/A | N/A | $11.44 | -$6.45 |
| Sep 2023 | N/A | N/A | $9.63 | -$6.13 |
| Jun 2023 | N/A | N/A | $10.64 | -$5.9 |
| Mar 2023 | 8.92 | -18.61% | $10.52 | $1.18 |
| Dec 2022 | 10.96 | 13.22% | $12.39 | $1.13 |
IRWD Price vs fair value
IRWD average PE ratio chart
What this chart measures
The Historical Valuation Regime chart shows where the stock's current valuation sits relative to its own historical valuation range over the selected lookback period.
This is a history-relative tool, not a market-relative percentile. It does not compare the stock to other companies. Instead, it compares each historical valuation reading to the stock's own past readings.
Percentile logic
The threshold lines are calculated them from the stock's real historical values using percentile interpolation. That is why some colored bands are narrow while others are wide: the band widths reflect how the stock actually traded through time.
Regime map
| Historical percentile | Regime | Chart meaning |
|---|---|---|
| 0-10 | Historically Low | Deep cheap zone |
| >10-25 | Below Average | Cheap relative to history |
| >25-75 | Average | Within the normal historical range |
| >75-90 | Above Average | Expensive relative to history |
| >90-100 | Historically High | Extreme or stretched valuation |
How to read each part
| Chart element | What it tells you |
|---|---|
| Main line | The actual historical valuation values over time for the selected metric. |
| Dashed horizontal lines | The stock's computed P10, P25, Median, P75, and P90 thresholds for the selected period. |
| Colored bands | The historical valuation zones between those thresholds. |
| Metric boxes | Current ratio, historical median, current percentile, and current regime. |
| Timeline strip | A condensed regime history showing how the stock moved between cheap, fair, and expensive states across each observation. |
Important metric definitions
Current Percentile is the percentile rank of the latest valid historical observation within the selected lookback range.
Current Regime is assigned directly from the latest observation's percentile bucket using the fixed 10 / 25 / 75 / 90 cutoffs shown above.
How to use it well
This chart is most useful for answering a narrow question: Is this stock trading high, low, or normal relative to its own history? It works best alongside growth, profitability, and forward-looking business analysis, because a stock can deserve a higher or lower regime if its business quality has changed.
The current PE ratio of IRWD is below the 3, 5 and 10-year averages.
PE comparison
With a P/E of 5.34, IRWD is below the Healthcare sector and the industry average. Compared to its Healthcare sector average of 23.69, Ironwood Pharmaceuticals's P/E is 77% lower.
IRWD PE vs peers
Frequently asked questions
What is Ironwood Pharmaceuticals's PE ratio?
As of Sep 23, 2026, IRWD stock has a price to earnings ratio of 5.34.
What is the 3-year average PE ratio for Ironwood Pharmaceuticals (IRWD)?
Over the last 3 years, the average price to earnings ratio for IRWD stock is 98.63.
What is the 5-year average PE ratio for Ironwood Pharmaceuticals (IRWD)?
Over the last 5 years, the average price to earnings ratio for IRWD stock is 49.49.
What is the highest PE ratio for IRWD?
In the last seven years, the Dec 2024 quarter recorded the highest quarterly PE ratio at 443.
How does the current PE ratio for IRWD compare to its historical average?
IRWD's current price to earnings ratio is 87% below its 7-year historical average.
Why is Ironwood Pharmaceuticals's PE ratio so low?
IRWD's stock price is trading at a lower multiple of earnings, which is why its PE ratio of 5.34 is considered low.
How is IRWD's PE ratio calculated (Ironwood Pharmaceuticals PE ratio formula)?
The PE ratio is calculated by dividing the most recent price of a stock by its trailing twelve months EPS. As of today (Sep 23, 2026), Ironwood Pharmaceuticals's stock price is $4.27. The earnings per share for the trailing twelve months (TTM) ending Jun 2026 is $0.8. Therefore, Ironwood Pharmaceuticals's P/E ratio for today is 5.34. PE RATIO(5.34) = STOCK PRICE($4.27) / TTM EPS($0.8)
All PE ratio stats are based on quarterly TTM periods, unless otherwise specified.