Based on the latest figures, Illumina reports a gross margin of 66.4%, an operating margin of 19.6%, an EBITDA margin of 30.8%, and a net margin of 18.4%. Net margin had the largest decline, falling by 11 percentage points, while the other available margins also weakened.
Over the last 3 years, Illumina recorded average margins of 64.39% gross, -7.04% operating, 1.52% EBITDA, and -10.97% net. The current gross, operating, EBITDA, and net margins are all above their three-year averages.
Year over year, gross, operating, EBITDA, and net margins all declined, with net margin showing the largest decrease at 11 percentage points.
Illumina's gross margin averaged 64.39% over the last 3 years. Compared with its three-year average, Illumina's current gross margin is 66.4% and is 2 percentage points above its three-year average. Over the last 3 years, Illumina's gross margin peaked at 66.5% in Jun 2025 and reached a low of 60.9% in Dec 2023.
Illumina recorded an average operating margin of -7.04% across the last 3 years. At present, the current operating margin for Illumina is 19.6%, 26.6 percentage points above its three-year average. The operating margin for Illumina moved between -60.2% in Jun 2024 and 30.2% in Jun 2025.
Across the last 3 years, Illumina's EBITDA margin came to 1.52%. The current EBITDA margin stands at 30.8%, 29.3 percentage points above its three-year average. EBITDA margin was highest at 41.6% in Jun 2025 and lowest at -57.1% in Jun 2024.
Illumina recorded an average net margin of -10.97% across the last 3 years. Illumina currently reports a net margin of 18.4%, 29.4 percentage points above its three-year average. Net margin was highest at 29.4% in Jun 2025 and lowest at -68.7% in Jun 2024.
Illumina's gross margin of 66.4% is above the industry and its peers average but below the Healthcare sector average. But compared to its Healthcare sector average of 68.5%, Illumina's gross margin is only 3.1% lower.
As of Jun 28, 2026, ILMN has a gross margin of 66.4%.
As of Jun 28, 2026, ILMN has an operating margin of 19.6%.
As of Jun 28, 2026, ILMN has an EBITDA margin of 30.8%.
As of Jun 28, 2026, ILMN has a net margin of 18.4%.
Across the last 3 years, ILMN averaged 64.4% gross, -7.0% operating, 1.5% EBITDA, and -11.0% net.
Looking back across 5 years, ILMN reached 69.7% gross in Jan 2022, 30.2% operating in Jun 2025, 41.6% EBITDA in Jun 2025, and 29.4% net in Jun 2025.
Looking back across 5 years, ILMN reached its lowest margins at 60.9% gross in Dec 2023, -99.6% operating in Apr 2023, -92.3% EBITDA in Apr 2023, and -100.9% net in Apr 2023.