CYRX Cryoport margins

Relative Growth: Rel. Growth:

Relative Strength: Rel. Strength:

Relative Valuation: Rel. Valuation:

Relative Profitability: Rel. Profitability: 20

Gross margin

46.9%

Operating margin

-20%

EBITDA margin

-3.6%

Net margin

-21.5%

Cryoport shows a gross margin of 46.9%, an operating margin of -20%, an EBITDA margin of -3.6%, and a net margin of -21.5%, although its operating margin is negative at -20%, its EBITDA margin is negative at -3.6%, and its net margin is negative at -21.5%. Among the available margins, operating margin improved the most and EBITDA margin declined the most, by 3 and 67.5 percentage points respectively.

CYRX margin history

Gross, operating, EBITDA and net margin trends

Over the last 3 years, Cryoport's margins averaged 45.91% gross, -58.31% operating, -10.88% EBITDA, and -35.58% net. All four current margins are above their three-year averages.

CYRX margin expansion

Year-over-year margin changes in percentage points

Compared with the same period last year, operating margin expanded by 3 percentage points, while EBITDA margin contracted by 67.5 percentage points and net margin by 62.9 percentage points.

Gross margin expansion

0pp

Operating margin expansion

3pp

EBITDA margin expansion

-67.5pp

Net margin expansion

-62.9pp

CYRX Gross margin

Cryoport recorded an average gross margin of 45.91% across the last 3 years. Cryoport currently reports a gross margin of 46.9%, 1 percentage points above its three-year average. Gross margin was highest at 47.2% in Mar 2026 and lowest at 44.2% in Mar 2024.

CYRX Operating margin

Over the last 3 years, the average operating margin for Cryoport was -58.31%. The latest operating margin for Cryoport is -20%, 38.3 percentage points above its three-year average. Cryoport's operating margin ranged from a low of -152% in Sep 2024 to a high of -20% in Sep 2026.

CYRX EBITDA margin

The average EBITDA margin for Cryoport was -10.88% during the last 3 years. At present, the current EBITDA margin for Cryoport is -3.6%, 7.3 percentage points above its three-year average. The EBITDA margin for Cryoport moved between -109.3% in Sep 2024 and 72.2% in Jun 2025.

CYRX Net margin

Over the last 3 years, Cryoport's net margin averaged -35.58%. The current net margin of -21.5% is 14.1 percentage points above its three-year average. During this period, net margin reached a high of 47.5% in Jun 2025 and a low of -146.8% in Sep 2024.

CYRX margin group comparison

Margins compared with peer-group, industry and sector averages

With a gross margin of 46.9%, CYRX stands higher than the Industrials sector and the industry average. Looking at the Industrials sector average of 32.5%, Cryoport's gross margin is 44% higher.

CYRX margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Cryoport's gross margin?

For the period ending Sep 30, 2026, CYRX recorded a gross margin of 46.9%.

What is Cryoport's operating margin?

As of Sep 30, 2026, CYRX has a negative operating margin of -20%.

What is Cryoport's EBITDA margin?

As of Sep 30, 2026, CYRX has a negative EBITDA margin of -3.6%.

What is Cryoport's net margin?

As of Sep 30, 2026, CYRX has a net margin of -21.5%.

What are the average margins of CYRX?

Over the past 3 years, CYRX reported average margins of 45.9% gross, -58.3% operating, -10.9% EBITDA, and -35.6% net.

What are the highest historical margins of CYRX?

Across the 5-year period, CYRX posted its highest margins at 47.2% gross in Mar 2026, -8% operating in Dec 2021, 72.2% EBITDA in Jun 2025, and 47.5% net in Jun 2025.

What are the lowest historical margins of CYRX?

Over the last 5 years, Cryoport's lowest margins were 42.6% gross in Mar 2022, -152% operating in Sep 2024, -114.8% EBITDA in Mar 2022, and -146.8% net in Sep 2024.