AXSM Axsome Therapeutics margins

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Relative Growth: Rel. Growth: 66
Relative Strength: Rel. Strength: 35
Relative Valuation: Rel. Valuation: 9
Relative Profitability: Rel. Profitability: 31
Gross margin
93.2%
Operating margin
-24%
EBITDA margin
-22.3%
Net margin
-24.7%

Axsome Therapeutics reports its operating margin is negative at -24%, its EBITDA margin is negative at -22.3%, and its net margin is negative at -24.7%, alongside a gross margin of 93.2%, an operating margin of -24%, an EBITDA margin of -22.3%, and a net margin of -24.7%. Net margin had the largest improvement, increasing by 25.2 percentage points, while the other available margins also improved.

AXSM margin history

Gross, operating, EBITDA and net margin trends

Over the last 3 years, Axsome Therapeutics recorded average margins of 91.51% gross, -62.85% operating, -61.1% EBITDA, and -64.91% net. The current gross, operating, EBITDA, and net margins are all above their three-year averages.

AXSM margin expansion

Year-over-year margin changes in percentage points

Gross margin expanded by 1.7 percentage points, operating margin by 22.2 percentage points, EBITDA margin by 23.9 percentage points, and net margin by 25.2 percentage points, led by net margin with an increase of 25.2 percentage points.

Gross margin expansion
1.7pp
Operating margin expansion
22.2pp
EBITDA margin expansion
23.9pp
Net margin expansion
25.2pp

AXSM Gross margin

Looking at the last 3 years, Axsome Therapeutics had an average gross margin of 91.51%. Against its three-year average, Axsome Therapeutics's gross margin is currently 93.2%, 1.7 percentage points above its three-year average. Looking back over the last 3 years, Axsome Therapeutics's gross margin reached 93.2% at its highest point in Jun 2026 and 90.1% at its lowest in Mar 2024.

AXSM Operating margin

The average operating margin for Axsome Therapeutics was -62.85% over the last 3 years. The current operating margin of -24% is 38.9 percentage points above its three-year average. The operating margin for Axsome Therapeutics moved between -116.6% in Mar 2024 and -24% in Jun 2026.

AXSM EBITDA margin

The average EBITDA margin for Axsome Therapeutics was -61.1% across the past 3 years. Right now, the current EBITDA margin for Axsome Therapeutics is -22.3%, 38.8 percentage points above its three-year average. The EBITDA margin for Axsome Therapeutics moved between -113.2% in Mar 2024 and -22.3% in Jun 2026.

AXSM Net margin

Across the last 3 years, Axsome Therapeutics's net margin averaged -64.91%. The current net margin stands at -24.7%, 40.2 percentage points above its three-year average. Net margin was highest at -24.7% in Jun 2026 and lowest at -118.1% in Mar 2024.

AXSM margin group comparison

Margins compared with peer-group, industry and sector averages

Axsome Therapeutics's gross margin of 93.2% is above the Healthcare sector and the industry average. Compared to its Healthcare sector average of 68.3%, Axsome Therapeutics's gross margin is 36% higher.

AXSM margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Axsome Therapeutics's gross margin?

The current gross margin for AXSM is 93.2% as of Jun 30, 2026.

What is Axsome Therapeutics's operating margin?

As of Jun 30, 2026, AXSM has a negative operating margin of -24%.

What is Axsome Therapeutics's EBITDA margin?

The current EBITDA margin for AXSM is -22.3% as of Jun 30, 2026.

What is Axsome Therapeutics's net margin?

The current net margin for AXSM is -24.7% as of Jun 30, 2026.

What are the average margins of AXSM?

Across the last 3 years, AXSM averaged 91.5% gross, -62.9% operating, -61.1% EBITDA, and -64.9% net.

What are the highest historical margins of AXSM?

Within the 5-year period, AXSM recorded its highest margins at 93.2% gross in Jun 2026, -24% operating in Jun 2026, -22.3% EBITDA in Jun 2026, and -24.7% net in Jun 2026.

What are the lowest historical margins of AXSM?

In the last 5 years, the lowest margins reported by AXSM were 88.7% gross in Sep 2022, -1,626.8% operating in Jun 2022, -1,602% EBITDA in Jun 2022, and -1,699.9% net in Jun 2022.