ALNY Alnylam Pharmaceuticals margins

Relative Growth: Rel. Growth:
Relative Strength: Rel. Strength:
Relative Valuation: Rel. Valuation:
Relative Profitability: Rel. Profitability: 98
Gross margin
79.7%
Operating margin
20.8%
EBITDA margin
24.5%
Net margin
16.8%

The Alnylam Pharmaceuticals shows a gross margin of 79.7%, an operating margin of 20.8%, an EBITDA margin of 24.5%, and a net margin of 16.8%. EBITDA margin improved the most, by 28.4 percentage points, while gross margin declined the most, by 3.9 percentage points.

ALNY margin history

Gross, operating, EBITDA and net margin trends

Over the last 3 years, Alnylam Pharmaceuticals's margins averaged 83.69% gross, 1.01% operating, 2.75% EBITDA, and -4.78% net. Currently, operating, EBITDA, and net margins are above their three-year averages, while gross margin is below its three-year average.

ALNY margin expansion

Year-over-year margin changes in percentage points

The largest positive change was in EBITDA and net margins, up 28.4 percentage points. Operating margin also expanded by 28.1 percentage points, while gross margin contracted by 3.9 percentage points.

Gross margin expansion
-3.9pp
Operating margin expansion
28.1pp
EBITDA margin expansion
28.4pp
Net margin expansion
28.4pp

ALNY Gross margin

Throughout the last 3 years, Alnylam Pharmaceuticals had an average gross margin of 83.69%. Currently, the current gross margin for Alnylam Pharmaceuticals is 79.7%, 4 percentage points below its three-year average. Looking back over the last 3 years, Alnylam Pharmaceuticals's gross margin reached 87% at its highest point in Jun 2024 and 79.7% at its lowest in Jun 2026.

ALNY Operating margin

Looking back over the last 3 years, Alnylam Pharmaceuticals recorded an average operating margin of 1.01%. Alnylam Pharmaceuticals's current operating margin is 20.8% and is 19.8 percentage points above its three-year average. The highest operating margin for Alnylam Pharmaceuticals was 20.8% in Jun 2026, while the lowest was -15.4% in Dec 2023.

ALNY EBITDA margin

The average EBITDA margin for Alnylam Pharmaceuticals was 2.75% in the last 3 years. The latest EBITDA margin for Alnylam Pharmaceuticals is 24.5%, 21.8 percentage points above its three-year average. The EBITDA margin for Alnylam Pharmaceuticals moved between -14.1% in Dec 2023 and 24.5% in Jun 2026.

ALNY Net margin

Alnylam Pharmaceuticals's net margin averaged -4.78% in the last 3 years. Compared with its three-year average, Alnylam Pharmaceuticals's current net margin is 16.8% and is 21.6 percentage points above its three-year average. Over the last 3 years, Alnylam Pharmaceuticals's net margin peaked at 16.8% in Jun 2026 and reached a low of -24.1% in Dec 2023.

ALNY margin group comparison

Margins compared with peer-group, industry and sector averages

With a gross margin of 79.7%, ALNY ranks higher than the Healthcare sector and its peers average but lower than the industry average. In comparison with the Healthcare sector average of 68.4%, Alnylam Pharmaceuticals's gross margin is 17% higher.

ALNY margin peer comparison

Compare margins with selected peers

Frequently asked questions

What is Alnylam Pharmaceuticals's gross margin?

As of Jun 30, 2026, ALNY has a gross margin of 79.7%.

What is Alnylam Pharmaceuticals's operating margin?

The current operating margin for ALNY is 20.8% as of Jun 30, 2026.

What is Alnylam Pharmaceuticals's EBITDA margin?

As of Jun 30, 2026, ALNY has an EBITDA margin of 24.5%.

What is Alnylam Pharmaceuticals's net margin?

For the period ending Jun 30, 2026, ALNY recorded a net margin of 16.8%.

What are the average margins of ALNY?

Alnylam Pharmaceuticals's gross, operating, EBITDA, and net margins averaged 83.7% gross, 1.0% operating, 2.8% EBITDA, and -4.8% net over the last 3 years.

What are the highest historical margins of ALNY?

Across the 5-year period, ALNY posted its highest margins at 87% gross in Jun 2024, 20.8% operating in Jun 2026, 24.5% EBITDA in Jun 2026, and 16.8% net in Jun 2026.

What are the lowest historical margins of ALNY?

Looking back across 5 years, ALNY reached its lowest margins at 79.7% gross in Jun 2026, -83.9% operating in Dec 2021, -97.3% EBITDA in Sep 2022, and -123% net in Sep 2022.