The Alnylam Pharmaceuticals shows a gross margin of 79.7%, an operating margin of 20.8%, an EBITDA margin of 24.5%, and a net margin of 16.8%. EBITDA margin improved the most, by 28.4 percentage points, while gross margin declined the most, by 3.9 percentage points.
Over the last 3 years, Alnylam Pharmaceuticals's margins averaged 83.69% gross, 1.01% operating, 2.75% EBITDA, and -4.78% net. Currently, operating, EBITDA, and net margins are above their three-year averages, while gross margin is below its three-year average.
The largest positive change was in EBITDA and net margins, up 28.4 percentage points. Operating margin also expanded by 28.1 percentage points, while gross margin contracted by 3.9 percentage points.
Throughout the last 3 years, Alnylam Pharmaceuticals had an average gross margin of 83.69%. Currently, the current gross margin for Alnylam Pharmaceuticals is 79.7%, 4 percentage points below its three-year average. Looking back over the last 3 years, Alnylam Pharmaceuticals's gross margin reached 87% at its highest point in Jun 2024 and 79.7% at its lowest in Jun 2026.
Looking back over the last 3 years, Alnylam Pharmaceuticals recorded an average operating margin of 1.01%. Alnylam Pharmaceuticals's current operating margin is 20.8% and is 19.8 percentage points above its three-year average. The highest operating margin for Alnylam Pharmaceuticals was 20.8% in Jun 2026, while the lowest was -15.4% in Dec 2023.
The average EBITDA margin for Alnylam Pharmaceuticals was 2.75% in the last 3 years. The latest EBITDA margin for Alnylam Pharmaceuticals is 24.5%, 21.8 percentage points above its three-year average. The EBITDA margin for Alnylam Pharmaceuticals moved between -14.1% in Dec 2023 and 24.5% in Jun 2026.
Alnylam Pharmaceuticals's net margin averaged -4.78% in the last 3 years. Compared with its three-year average, Alnylam Pharmaceuticals's current net margin is 16.8% and is 21.6 percentage points above its three-year average. Over the last 3 years, Alnylam Pharmaceuticals's net margin peaked at 16.8% in Jun 2026 and reached a low of -24.1% in Dec 2023.
With a gross margin of 79.7%, ALNY ranks higher than the Healthcare sector and its peers average but lower than the industry average. In comparison with the Healthcare sector average of 68.4%, Alnylam Pharmaceuticals's gross margin is 17% higher.
As of Jun 30, 2026, ALNY has a gross margin of 79.7%.
The current operating margin for ALNY is 20.8% as of Jun 30, 2026.
As of Jun 30, 2026, ALNY has an EBITDA margin of 24.5%.
For the period ending Jun 30, 2026, ALNY recorded a net margin of 16.8%.
Alnylam Pharmaceuticals's gross, operating, EBITDA, and net margins averaged 83.7% gross, 1.0% operating, 2.8% EBITDA, and -4.8% net over the last 3 years.
Across the 5-year period, ALNY posted its highest margins at 87% gross in Jun 2024, 20.8% operating in Jun 2026, 24.5% EBITDA in Jun 2026, and 16.8% net in Jun 2026.
Looking back across 5 years, ALNY reached its lowest margins at 79.7% gross in Jun 2026, -83.9% operating in Dec 2021, -97.3% EBITDA in Sep 2022, and -123% net in Sep 2022.