VRTX Vertex Pharmaceuticals PE ratio, current and historical analysis
- Stocks
- Healthcare
- NASDAQ: VRTX
- PE Ratio
As of Nov 6, 2025, the VRTX stock has a PE ratio of 29.14. The calculation is based on the latest EPS of $14.31 and the stock price of $417 per share.
VRTX PE ratio history
The mean historical PE ratio of Vertex Pharmaceuticals over the last nine years is 51.74. The current 29.14 price-to-earnings ratio is 44% less than the historical average. Analyzing the last nine years, VRTX's PE ratio reached its highest point in the Sep 2017 quarter at 190.05, with a price of $152.04 and an EPS of $0.8. The Dec 2018 quarter saw the lowest point at 20.11, with a price of $165.71 and an EPS of $8.24.
Vertex Pharmaceuticals PE ratio by year
Maximum annual increase: 137.74% in 2019
Maximum annual decrease: -85.78% in 2018
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| 2024 | N/A | N/A | $402.7 | -$2.08 |
| 2023 | 28.96 | 30.04% | $406.89 | $14.05 |
| 2022 | 22.27 | -7.82% | $288.78 | $12.97 |
| 2021 | 24.16 | 6.71% | $219.6 | $9.09 |
| 2020 | 22.64 | -52.65% | $236.34 | $10.44 |
| 2019 | 47.81 | 137.74% | $218.95 | $4.58 |
| 2018 | 20.11 | -85.78% | $165.71 | $8.24 |
| 2017 | 141.38 | N/A | $149.86 | $1.06 |
| 2016 | N/A | N/A | $73.67 | -$0.46 |
| 2015 | N/A | N/A | $125.83 | -$2.31 |
| 2014 | N/A | N/A | $118.8 | -$3.14 |
| 2013 | N/A | N/A | $74.3 | -$1.98 |
| 2012 | N/A | N/A | $41.9 | -$0.5 |
| 2011 | 237.21 | N/A | $33.21 | $0.14 |
| 2010 | N/A | N/A | $35.03 | -$3.77 |
Vertex Pharmaceuticals PE ratio by quarter (TTM)
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| Sep 2025 | 27.37 | -13.19% | $391.64 | $14.31 |
| Jun 2025 | 31.53 | N/A | $445.2 | $14.12 |
| Mar 2025 | N/A | N/A | $484.82 | -$3.82 |
| Dec 2024 | N/A | N/A | $402.7 | -$2.08 |
| Sep 2024 | N/A | N/A | $465.08 | -$1.85 |
| Jun 2024 | N/A | N/A | $468.72 | -$1.89 |
| Mar 2024 | 26.83 | -7.35% | $418.01 | $15.58 |
| Dec 2023 | 28.96 | 12.16% | $406.89 | $14.05 |
| Sep 2023 | 25.82 | -3.94% | $347.74 | $13.47 |
| Jun 2023 | 26.88 | 8.43% | $351.91 | $13.09 |
| Mar 2023 | 24.79 | 11.32% | $315.07 | $12.71 |
| Dec 2022 | 22.27 | -1.55% | $288.78 | $12.97 |
| Sep 2022 | 22.62 | 0.09% | $289.54 | $12.8 |
| Jun 2022 | 22.6 | -17.22% | $281.79 | $12.47 |
| Mar 2022 | 27.3 | 13% | $260.97 | $9.56 |
VRTX Price vs fair value
VRTX average PE ratio chart
VRTX's current PE ratio is higher than the 3 and 5-year averages, but it is under its 10-year average.
PE comparison
Vertex Pharmaceuticals's price to earnings (P/E) of 29.14 is higher than the Healthcare sector, the industry and its peers average. Looking at the Healthcare sector average of 25.01, Vertex Pharmaceuticals's price to earnings (P/E) is 17% higher.
VRTX PE vs peers
When compared to its peer ABBV, VRTX's PE ratio is lower, but it is higher than JNJ's and MRK's. Vertex Pharmaceuticals is currently trading at a higher PE ratio (29.14) than its peers average of 17.68.
| Stock name | PE ratio | Market cap |
|---|---|---|
| MRK Merck & Co Inc | 13.2 | $214.26B |
| BMY Bristol Myers Squibb Co | 15.7 | $94.93B |
| JNJ Johnson & Johnson | 17.93 | $450.47B |
| GILD Gilead Sciences Inc | 24.44 | $153.12B |
| VRTX Vertex Pharmaceuticals Inc | 29.09 | $105.61B |
| ABBV AbbVie Inc | 164.69 | $387.13B |
| ENTA Enanta Pharmaceuticals Inc | N/A | $230.88M |
Frequently asked questions
What is Vertex Pharmaceuticals's PE ratio?
The price to earnings ratio for VRTX stock is 29.14 as of Nov 6, 2025.
What is the 3-year average PE ratio for Vertex Pharmaceuticals (VRTX)?
Over the last 3 years, the average PE ratio for VRTX stock is 26.81.
What is the 5-year average PE ratio for Vertex Pharmaceuticals (VRTX)?
Over the last 5 years, the average PE ratio for VRTX stock is 25.11.
What is the highest PE ratio for VRTX?
The highest quarterly PE ratio in the last nine years has been 190.05 and it was in the Sep 2017 quarter.
How does the current PE ratio for VRTX compare to its historical average?
VRTX's current price to earnings ratio is 44% below its 9-year historical average.
How is VRTX's PE ratio calculated (Vertex Pharmaceuticals PE ratio formula)?
The P/E ratio is calculated by taking the latest stock price and dividing it by the earnings per share(EPS) for the last 12 months. As of today (Nov 6, 2025), Vertex Pharmaceuticals's share price is $417. The company's earnings per share for the trailing twelve months (TTM) ending Sep 2025 is $14.31. Therefore, Vertex Pharmaceuticals's price to earnings ratio for today is 29.14. PE RATIO(29.14) = STOCK PRICE($417) / TTM EPS($14.31)
All PE ratio stats are based on quarterly TTM periods, unless otherwise specified.