PBYI
Puma Biotechnology
PE ratio, current and historical analysis
- Stocks
- Healthcare
- NASDAQ: PBYI
- PE Ratio
As at Sep 23, 2026, the PBYI stock has a price-to-earnings ratio of 17.19. This is based on the current EPS of $0.54 and the stock price of $9.28 per share. An increase of 55% has been recorded in the PE ratio compared to the average of 11.1 of the last four quarters.
PBYI PE ratio history
The mean historical PE ratio of Puma Biotechnology over the last four years is 13.14. The current 17.19 P/E ratio is 31% higher than the historical average. In the past four years, PBYI's PE ratio peaked in the Sep 2023 quarter at 37.57, with a price of $2.63 and an EPS of $0.07. The Jun 2025 quarter marked the lowest point at 3.5, with a price of $3.43 and an EPS of $0.98.
Puma Biotechnology PE ratio by year
Maximum annual increase: 95.12% in 2025
Maximum annual decrease: -47.72% in 2024
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| 2025 | 9.6 | 95.12% | $5.95 | $0.62 |
| 2024 | 4.92 | -47.72% | $3.05 | $0.62 |
| 2023 | 9.41 | N/A | $4.33 | $0.46 |
| 2022 | N/A | N/A | $4.23 | $0 |
| 2021 | N/A | N/A | $3.04 | -$0.72 |
| 2020 | N/A | N/A | $10.26 | -$1.52 |
| 2019 | N/A | N/A | $8.75 | -$1.95 |
| 2018 | N/A | N/A | $20.35 | -$2.99 |
| 2017 | N/A | N/A | $98.85 | -$7.85 |
| 2016 | N/A | N/A | $30.7 | -$8.29 |
| 2015 | N/A | N/A | $78.4 | -$7.45 |
| 2014 | N/A | N/A | $189.27 | -$4.73 |
| 2013 | N/A | N/A | $103.53 | -$1.9 |
| 2012 | N/A | N/A | $18.75 | -$3.42 |
| 2011 | N/A | N/A | N/A | -$1.32 |
Puma Biotechnology PE ratio by quarter (TTM)
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| Jun 2026 | 15.02 | 17.53% | $8.11 | $0.54 |
| Mar 2026 | 12.78 | 33.13% | $6.39 | $0.5 |
| Dec 2025 | 9.6 | 35.59% | $5.95 | $0.62 |
| Sep 2025 | 7.08 | 102.29% | $5.31 | $0.75 |
| Jun 2025 | 3.5 | -8.85% | $3.43 | $0.98 |
| Mar 2025 | 3.84 | -21.95% | $2.96 | $0.77 |
| Dec 2024 | 4.92 | -7.34% | $3.05 | $0.62 |
| Sep 2024 | 5.31 | -69.06% | $2.55 | $0.48 |
| Jun 2024 | 17.16 | 6.85% | $3.26 | $0.19 |
| Mar 2024 | 16.06 | 70.67% | $5.3 | $0.33 |
| Dec 2023 | 9.41 | -74.95% | $4.33 | $0.46 |
| Sep 2023 | 37.57 | N/A | $2.63 | $0.07 |
| Jun 2023 | N/A | N/A | $3.53 | -$0.06 |
| Mar 2023 | 30.9 | N/A | $3.09 | $0.1 |
| Dec 2022 | N/A | N/A | $4.23 | $0 |
PBYI Price vs fair value
PBYI average PE ratio chart
What this chart measures
The Historical Valuation Regime chart shows where the stock's current valuation sits relative to its own historical valuation range over the selected lookback period.
This is a history-relative tool, not a market-relative percentile. It does not compare the stock to other companies. Instead, it compares each historical valuation reading to the stock's own past readings.
Percentile logic
The threshold lines are calculated them from the stock's real historical values using percentile interpolation. That is why some colored bands are narrow while others are wide: the band widths reflect how the stock actually traded through time.
Regime map
| Historical percentile | Regime | Chart meaning |
|---|---|---|
| 0-10 | Historically Low | Deep cheap zone |
| >10-25 | Below Average | Cheap relative to history |
| >25-75 | Average | Within the normal historical range |
| >75-90 | Above Average | Expensive relative to history |
| >90-100 | Historically High | Extreme or stretched valuation |
How to read each part
| Chart element | What it tells you |
|---|---|
| Main line | The actual historical valuation values over time for the selected metric. |
| Dashed horizontal lines | The stock's computed P10, P25, Median, P75, and P90 thresholds for the selected period. |
| Colored bands | The historical valuation zones between those thresholds. |
| Metric boxes | Current ratio, historical median, current percentile, and current regime. |
| Timeline strip | A condensed regime history showing how the stock moved between cheap, fair, and expensive states across each observation. |
Important metric definitions
Current Percentile is the percentile rank of the latest valid historical observation within the selected lookback range.
Current Regime is assigned directly from the latest observation's percentile bucket using the fixed 10 / 25 / 75 / 90 cutoffs shown above.
How to use it well
This chart is most useful for answering a narrow question: Is this stock trading high, low, or normal relative to its own history? It works best alongside growth, profitability, and forward-looking business analysis, because a stock can deserve a higher or lower regime if its business quality has changed.
The current PE ratio of PBYI is higher than its 3, 5 and 10-year historical averages.
PE comparison
Puma Biotechnology's P/E of 17.19 is above the industry average but below the Healthcare sector average. In comparison with its Healthcare sector average of 23.69, Puma Biotechnology's P/E is 27% lower.
PBYI PE vs peers
Frequently asked questions
What is Puma Biotechnology's PE ratio?
The price to earnings ratio for PBYI stock is 17.19 as of Sep 23, 2026.
What is the 3-year average PE ratio for Puma Biotechnology (PBYI)?
Over the last 3 years, the average price to earnings ratio for PBYI stock is 11.85.
What is the 5-year average PE ratio for Puma Biotechnology (PBYI)?
Over the last 5 years, the average price to earnings ratio for PBYI stock is 13.14.
What is the highest PE ratio for PBYI?
The highest quarterly PE ratio in the last four years has been 37.57 and it was in the Sep 2023 quarter.
How does the current PE ratio for PBYI compare to its historical average?
PBYI's current price to earnings ratio is 31% above its 4-year historical average.
How is PBYI's PE ratio calculated (Puma Biotechnology PE ratio formula)?
The P/E ratio is obtained by dividing the latest price of a stock by its trailing twelve months EPS. As of today (Sep 23, 2026), Puma Biotechnology's stock price is $9.28. The earnings per share for the trailing twelve months (TTM) ending Jun 2026 is $0.54. Therefore, Puma Biotechnology's PE ratio for today is 17.19. PE RATIO(17.19) = STOCK PRICE($9.28) / TTM EPS($0.54)
All PE ratio stats are based on quarterly TTM periods, unless otherwise specified.