The P/E ratio for Harmony Biosciences Holdings stock stands at 12.69 as of Jun 3, 2026. This takes into account the latest EPS of $2.53 and stock price of $32.1. An increase of 18% has been observed in the PE ratio compared to its average of 10.8 of the past four quarters.
Over the last six years, the average PE ratio of Harmony Biosciences Holdings has been 24.69. The current 12.69 price-to-earnings ratio is 49% less than the historical average. Analyzing the last six years, HRMY's PE ratio reached its highest point in the Mar 2021 quarter at 103.25, with a price of $33.04 and an EPS of $0.32. The Sep 2025 quarter saw the lowest point at 8.53, with a price of $27.56 and an EPS of $3.23.
Maximum annual increase: 0.89% in 2025
Maximum annual decrease: -74.74% in 2022
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| 2025 | 13.56 | 0.89% | $37.42 | $2.76 |
| 2024 | 13.44 | -9.68% | $34.41 | $2.56 |
| 2023 | 14.88 | -17.1% | $32.3 | $2.17 |
| 2022 | 17.95 | -74.74% | $55.1 | $3.07 |
| 2021 | 71.07 | N/A | $42.64 | $0.6 |
| 2020 | N/A | N/A | $36.15 | -$2.48 |
| 2019 | N/A | N/A | N/A | -$24.07 |
| 2018 | N/A | N/A | N/A | -$7.91 |
| Year | PE ratio | PE change | Price | EPS |
|---|---|---|---|---|
| Mar 2026 | 11.07 | -18.36% | $28.01 | $2.53 |
| Dec 2025 | 13.56 | 58.97% | $37.42 | $2.76 |
| Sep 2025 | 8.53 | -14.7% | $27.56 | $3.23 |
| Jun 2025 | 10 | -19.55% | $31.6 | $3.16 |
| Mar 2025 | 12.43 | -7.51% | $33.19 | $2.67 |
| Dec 2024 | 13.44 | -27.74% | $34.41 | $2.56 |
| Sep 2024 | 18.6 | 22.05% | $40 | $2.15 |
| Jun 2024 | 15.24 | 6.65% | $30.17 | $1.98 |
| Mar 2024 | 14.29 | -3.97% | $33.58 | $2.35 |
| Dec 2023 | 14.88 | 14.46% | $32.3 | $2.17 |
| Sep 2023 | 13 | 24.16% | $32.77 | $2.52 |
| Jun 2023 | 10.47 | 2.25% | $35.19 | $3.36 |
| Mar 2023 | 10.24 | -42.95% | $32.65 | $3.19 |
| Dec 2022 | 17.95 | 6.59% | $55.1 | $3.07 |
| Sep 2022 | 16.84 | -66.16% | $44.29 | $2.63 |
The Historical Valuation Regime chart shows where the stock's current valuation sits relative to its own historical valuation range over the selected lookback period.
This is a history-relative tool, not a market-relative percentile. It does not compare the stock to other companies. Instead, it compares each historical valuation reading to the stock's own past readings.
The threshold lines are calculated them from the stock's real historical values using percentile interpolation. That is why some colored bands are narrow while others are wide: the band widths reflect how the stock actually traded through time.
| Historical percentile | Regime | Chart meaning |
|---|---|---|
| 0-10 | Historically Low | Deep cheap zone |
| >10-25 | Below Average | Cheap relative to history |
| >25-75 | Average | Within the normal historical range |
| >75-90 | Above Average | Expensive relative to history |
| >90-100 | Historically High | Extreme or stretched valuation |
| Chart element | What it tells you |
|---|---|
| Main line | The actual historical valuation values over time for the selected metric. |
| Dashed horizontal lines | The stock's computed P10, P25, Median, P75, and P90 thresholds for the selected period. |
| Colored bands | The historical valuation zones between those thresholds. |
| Metric boxes | Current ratio, historical median, current percentile, and current regime. |
| Timeline strip | A condensed regime history showing how the stock moved between cheap, fair, and expensive states across each observation. |
Current Percentile is the percentile rank of the latest valid historical observation within the selected lookback range.
Current Regime is assigned directly from the latest observation's percentile bucket using the fixed 10 / 25 / 75 / 90 cutoffs shown above.
This chart is most useful for answering a narrow question: Is this stock trading high, low, or normal relative to its own history? It works best alongside growth, profitability, and forward-looking business analysis, because a stock can deserve a higher or lower regime if its business quality has changed.
The current PE ratio of HRMY is under its 3 and 5-year averages.
With a price to earnings (P/E) of 12.69, HRMY stands lower than the Healthcare sector and the industry average. Looking at the Healthcare sector average of 23.02, Harmony Biosciences Holdings's price to earnings (P/E) is 45% lower.
| Stock name | PE ratio | Market cap |
|---|---|---|
| HRMY Harmony Biosciences Holdings Inc | 13.03 | $1.91B |
| OPK Opko Health Inc | N/A | $1.1B |
| ORGO Organogenesis Holdings Inc | N/A | $319.11M |
As of Jun 3, 2026, HRMY stock has a price to earnings ratio of 12.69.
The 3-year average PE ratio for HRMY stock is 12.96.
The 5-year average PE ratio for HRMY stock is 20.76.
Over the last six years, the quarterly PE ratio reached its highest level at 103.25 in the Mar 2021 quarter.
HRMY's price to earnings ratio is currently 49% below its 6-year historical average.
The P/E ratio is calculated by dividing the latest price of a stock by its trailing twelve months EPS. As of today (Jun 3, 2026), Harmony Biosciences Holdings's share price is $32.1. The company's earnings per share for the trailing twelve months (TTM) ending Mar 2026 is $2.53. Therefore, Harmony Biosciences Holdings's price to earnings ratio for today is 12.69. PE RATIO(12.69) = STOCK PRICE($32.1) / TTM EPS($2.53)
All PE ratio stats are based on quarterly TTM periods, unless otherwise specified.